Erespal official instructions for use for children. Erespal for children: instructions for use for children and specific purposes

Erespal is a modern drug used to treat coughs that occur as a result of various inflammatory processes and infections in the respiratory tract. Cough is one of the most unpleasant consequences of the flu. And although by its nature it is one of defense mechanisms, helping the body fight infection, this does not make it any easier. Often a cough is accompanied by spasm of the bronchi and obstruction of their patency (bronchoconstriction). Cough is especially dangerous for young children, for whom it causes great suffering.

Description

The main component of the drug is fenspiride hydrochloride. This substance has a triple effect on the body. First, it reduces inflammation. Secondly, it acts on histamine receptors and thereby blocks the production of mucus in the bronchi. Thirdly, it has an antispasmodic effect. Therefore, the use of Erespal contributes to the expansion of the bronchi.

The principle of action of the drug is fundamentally different from the principle of action of other antitussive drugs. They are divided into two large groups. Some of them affect the so-called dry cough, that is, a cough without the formation of sputum. Others help to liquefy this phlegm and remove it from the body.
Erespal does not belong to any of these groups. But this does not prevent him from being highly effective. The reason is that the drug fights not so much the consequences of inflammation as it suppresses the mechanism of its occurrence. In addition, fenspiride suppresses the cough reflex without affecting the corresponding center of the brain.

One of the advantages of the drug is that it can also be useful for viral respiratory infections (ARVI), for which antibiotics do not work. This is achieved due to the fact that it has a strong anti-inflammatory effect.

Most of the drug is excreted through the kidneys, and about one tenth through the intestines.

Indications for use:

• laryngitis
• pharyngitis
• bronchial asthma
• flu
• sinusitis

A natural question arises: can Erespal serve as a replacement for treating the body with antibiotics? Of course no. Erespal is primarily an antitussive drug and cannot be the only method of treating infectious diseases.

Release forms and composition

The drug is available in two dosage forms: tablets with a dosage of 80 mg and Erespal for children in the form of syrup in 150 ml bottles. Each box of the drug contains detailed instructions, which should be read carefully.

Compound

Fenspiride hydrochloride is a rather bitter substance. Therefore, the syrup contains many sweeteners and flavorings so that children take the medicine with pleasure.

Composition of the tablet:

• fenspiride
• calcium phosphate disubstituted
• hypromellose
• povidone
• colloidal anhydrous silicon
• Magnesium stearate
• titanium dioxide
• glycerol
• macrogol 6000

The syrup is sold in 150 ml bottles. 1 ml of syrup contains 2 mg of fenspiride.

Other substances included in the syrup:

• honey flavor
• licorice root extract
• glucose
• anise oil
• vanillin extract
• glycerol
• Sunset Yellow S dye
• methyl parahydroxybenzoate
• propyl parahydroxybenzoate
• saccharin
• sucrose
• potassium sorbate
• distilled water

Erespal is produced by the French pharmaceutical company Laboratorium Servier. This is a proven and reliable supplier. However, as with many other imported medicines, the price of the drug may seem too high. In this case, you can look for analogues of the drug containing fenspiride. Such drugs include the drugs Fenspiride, Erispirus, Codestim, Fosidal and some others. However, when choosing an effective medicine You should focus not only on prices, since drugs of lower cost may be inferior in quality. Other antitussive drugs can hardly replace Erespal, since they do not have an antihistamine and antispasmodic effect.

The drug is sold in pharmacies with a prescription. Erespal is stored at room temperature. The shelf life of tablets is 3 years, syrup - 2 years.

Erespal, instructions for use

Before taking Erespal, you should read the instructions for use that come with the drug. The drug is very well absorbed by the body when taken orally and begins to act after just a few hours. For tablets, the therapeutic effect begins to appear after 2-3 hours, for syrup – after an hour. The maximum effect of the medicine reaches after 6 hours. In case of overdose, consult a doctor.

Instructions for use of tablets for adults

According to the instructions, you need to take two 80 mg tablets per day. In severe cases of the disease, the doctor may increase the frequency of administration to 3 times a day. The duration of treatment is also determined by the doctor. In most cases, improvement occurs within 2-3 days. According to Erespal's instructions, the drug is usually taken before meals.

Erespal tablets are intended for adults only. Children under 14 years of age are prohibited from taking them. To treat children, it is better to use Erespal in syrup form, while following the instructions.

Instructions for use of syrup for children

The dosage of syrup for children depends on the child’s body weight. It must be selected so that the daily dose does not exceed 4 mg/kg of body weight. Typically, for children weighing less than 10 kg, syrup is prescribed at 2-4 teaspoons per day, and for children heavier than 10 kg - 2-4 tablespoons. Erespal syrup can be taken by children from 2 years of age. A child under 2 years of age should not be given the drug in any form. Adults should take Erespal syrup 2-3 tablespoons (45-90 ml) per day.

Contraindications

The drug has very few contraindications. First of all, it is not recommended to give the drug to children under 2 years of age. Secondly, this is individual intolerance to the active substance and auxiliary components included in the drug. Since the syrup contains sucrose, it is contraindicated for patients diabetes mellitus. Such patients should take tablets.

Interaction with other drugs

If you are taking other cough suppressants at the same time, you should consult your doctor. It is not recommended to take Erespal with sedatives and alcohol, since the drug, as an antihistamine, has its own sedative effect, which will enhance the sedative effect of other drugs.

Also, in the case of simultaneous use of Erespal, alcohol and other sedatives, one should be wary of a deterioration in the reaction rate. This should be taken into account by those who drive vehicles.

Side effects

Rarely may be observed:

• allergic reactions, nausea, drowsiness and lethargy
• moderate tachycardia
• gastrointestinal disorders
• epigastric pain
• drowsiness
• erythema
• hives
• angioedema

P N012547/02

Tradename

ERESPAL®

International nonproprietary name

fenspiride

Dosage form ERESPAL®

syrup

Composition of ERESPAL® syrup

100 ml of syrup contains active substance: fenspiride hydrochloride - 0.2 g.

Excipients:flavoring composition with hints of honey smell 0.500 g, licorice root extract 0.200 g, vanilla tincture 0.400 g, glycerol 22.5 g, sunset yellow dye (Sunset yellow)S)0.01 g, methyl parahydroxybenzoate 0.09 g, propyl parahydroxybenzoate 0.035 g; saccharin 0.045 g, sucrose 60.0 g, potassium sorbate 0.19 g; purified water up to 100 ml.

Description ERESPAL® syrup

Transparent orange liquid; sediment may form, disappearing when shaken.

Pharmacotherapeutic group

Anti-inflammatory, antibronchoconstrictor agent.

Code ATX:

R03DX03

Pharmacological properties

Pharmacodynamics

An anti-inflammatory agent, has an antiexudative effect, prevents the development of bronchospasm. Shows antagonism with mediators of inflammation and allergy: serotonin, histamine (blockade of H1-histamine receptors), bradykinin. Has a myotropic antispasmodic effect. When administered in large doses, it reduces the production of various inflammatory factors (cytokines, arachidonic acid derivatives, free radicals).

Pharmacokinetics

Well absorbed from the gastrointestinal tract.

The maximum concentration in blood plasma after oral administration is achieved after 2.3 ± 2.5 hours (from 0.5 to 8 hours). The half-life is 12 hours.

It is excreted mainly by the kidneys (90%), 10% through the intestines.

Indications ERESPAL® syrup

Diseases of the upper and lower respiratory tract:

Rhinopharyngitis and laryngitis;

Tracheobronchitis;

Bronchitis (with or without chronic respiratory failure);

Bronchial asthma (as part of complex therapy);

Respiratory phenomena (cough, hoarseness, sore throat) with measles, whooping cough and influenza;

At infectious diseases respiratory tract, accompanied by cough, when standard antibiotic therapy is indicated.

Otitis and sinusitis of various etiologies.

Contraindications

Increased sensitivity to active substance and/or any of the components of the drug.

Children under 2 years of age.

Carefully:

Patients with fructose intolerance, glucose-galactose malabsorption, sucrase/isomaltase deficiency (due to the presence of sucrose in Erespal® syrup), patients with diabetes mellitus (due to the presence of sucrose in Erespal® syrup).

Pregnancy and lactation period

There are no or limited data on the use of Erespal® in pregnant women. Taking the drug during pregnancy is not recommended.

Fenspiride therapy is not a reason to terminate an ongoing pregnancy.

Erespal® should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

Directions for use and dosage of ERESPAL® syrup

Inside.

Shake before use.

Adults and teenagers:

From 3 to 6 tablespoons of syrup (45-90 ml) per day, take before meals.

Children from 2 years old:

Body weight up to 10 kg: 2 to 4 teaspoons of syrup per day (or 10-20 ml), can be added to a feeding bottle

Body weight more than 10 kg: from 2 to 4 tablespoons of syrup per day (or 30-60 ml), taken before meals. 1 tablespoon (15 ml of syrup) contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.

1 teaspoon (5 ml of syrup) contains 10 mg of fenspiride hydrochloride and 3 g of sucrose.

The duration of treatment is determined by the doctor.

Side effect

INFORM YOUR DOCTOR ABOUT ANY ADVERSE REACTIONS AND SENSATIONS YOU HAVE, INCLUDING ANY ADVERSE REACTIONS AND SENSATIONS NOT MENTIONED IN THIS INSTRUCTION, AS WELL AS CHANGES IN LABORATORY VALUES DURING PHONETHERAPY.

The most common adverse reactions to medicinal product Erespal® are observed from the digestive system. The frequency of adverse reactions that may occur during therapy is given in the following gradation: very often (>1/10); often (>1/100,<1/10); нечасто (>1/1000, <1/100); редко (>1/10000, <1/1000); очень редко (<1/10000) и неустановленной частоты (частота не может быть подсчитана по доступным данным).

From the cardiovascular system:

Rarely: moderate tachycardia, the severity of which decreases with decreasing dose of the drug.

Unspecified frequency*:palpitations, hypotension, possibly associated with tachycardia.

From the digestive system:

Often: gastrointestinal disorders, nausea, epigastric pain.

Unspecified frequency*: diarrhea, vomiting.

From the central nervous system:

Rarely: drowsiness.

Unspecified frequency*:dizziness.

Common disorders and symptoms:

Unspecified frequency*:asthenia, increased fatigue.

For the skin and subcutaneous fat:

Rarely: erythema, rash, urticaria, angioedema, fixed erythema pigmentosa.

Unspecified frequency*:pruritus, toxic epidermal necrolysis, Stevens-Johnson syndrome.

*Post-registration data.

Risk of developing hypersensitivity reactions to Sunset yellow dyeS,included in the drug.

Overdose

In case of an overdose of the drug (cases of overdose have been reported when taking the drug at a dose of more than 2320 mg), you should immediately seek medical help.

Symptoms: drowsiness or agitation, nausea, vomiting, sinus tachycardia.

Treatment: gastric lavage, electrocardiogram (ECG) monitoring. Maintaining vital body functions.

Interaction with other drugs

No special studies have been conducted on the interaction of fenspiride with other drugs.

Due to the possible enhancement of the sedative effect when taking histamine H1 receptor blockers, it is not recommended to use Erespal® syrup in combination with drugs that have a sedative effect, or in combination with alcohol.

special instructions

The drug contains parabens (parahydroxybenzoates), as a result of which taking this drug can provoke the development of allergic reactions, including delayed ones.

When prescribing the drug to patients with diabetes, it is necessary to take into account that Erespal® syrup contains sucrose (1 teaspoon - 3 g of sucrose = 0.3 XE; 1 tbsp. spoon - 9 g of sucrose = 0.9 XE).

No studies have been conducted to study the effect of Erespal® on the ability to drive vehicles and operate machinery. Patients should be aware of the possible development of drowsiness while taking Erespal®, especially at the beginning of therapy or when combined with alcohol intake, and should be careful when driving vehicles and when performing work that requires a high speed of psychomotor reactions.

Release form ERESPAL® syrup

Produced by Servier Industry Laboratory, France:

Syrup.2 mg/ml. 150 ml of syrup in a brown plastic bottle (PVC) with a plastic cap with tamper evident. One bottle with instructions for medical use is placed in a cardboard box.

Erespal (fenspiride) is a drug with a bronchodilator and antispasmodic effect, which is often used in the complex therapy of bronchial asthma. It has a clinically proven ability to increase the activity of cilia of the bronchial ciliated epithelium, normalize the volume of bronchial secretions and reduce its viscosity. Effectively relieves bronchial obstruction and restores pulmonary gas exchange.

• Not recommended for treatment of pregnant and lactating women. Children over 2 years of age can be prescribed only in the form of syrup.
• Included in the list of vital drugs.
• Available in two dosage forms for oral use: syrup and tablets.

Pharmgroup

A drug with antibronchoconstrictor and anti-inflammatory activity.
Pharmacological group of the active substance of the drug (fenspiride): H1-antihistamines.

Composition of the drug

	Active substance	Excipients	Shell
Pills	80 mg fenspiride hydrochloride	104.5 mg calcium hydrogen phosphate, 100 mg hypromellose, 0.5 mg colloidal anhydrous silicon dioxide, 12.8 mg povidone-K30, 2.2 mg magnesium stearate.	0.841 mg titanium dioxide, 0.263 mg macrogol 6000, 0.263 mg glycerol, 0.263 mg magnesium stearate, 4.37 mg hypromellose.
Syrup	200 mg fenspiride hydrochloride (per 1 ml syrup - 2 mg fenspiride)	500 mg honey flavor, 400 mg vanilla tincture, 200 mg licorice root extract, 10 mg Sunset S yellow, 90 mg methyl parahydroxybenzoate, 22.5 g glycerol, 60 mg sucrose, 45 mg saccharin, 35 mg propyl parahydroxybenzoate, 190 mg potassium sorbate, purified water to a volume of 100 ml.	—

Release form, price

• Erespal syrup: transparent liquid, orange in color, in brown plastic bottles of 150 or 250 ml, in cardboard packaging. Price:
  syrup 150 ml - 210-264 rubles,
  syrup 250 ml - 333-428 rub.
• Erespal tablets: white, round, biconvex, film-coated tablets, 15 pieces in a blister, 2 blisters in a cardboard pack (30 tablets).
  Price: 299-430 rub.

pharmachologic effect

According to the instructions for use of Erespal, the active ingredient of the drug - fenspiride - has a pronounced anti-inflammatory and anti-bronchoconstrictor effect, due to a decrease in the production of the main biologically active substances that play a key role in the development of the inflammatory reaction and bronchospasm: cytokines, free radicals, arachidonic acid metabolites.

Inhibits the metabolism of arachidonic acid, while simultaneously blocking histamine H1 receptors, since it is histamine that stimulates the chemical reactions of converting arachidonic acid into final metabolites-inflammatory factors. Reduces the production of other inflammatory mediators - serotonin and bradykinin.

Blocks α-adrenergic receptors, the activation of which increases the secretion of the bronchial glands. The complex effect of fenspiride reduces the pathological influence of a number of factors that promote hypersecretion of anti-inflammatory substances and cause obstruction of the bronchial tree. It has a pronounced antispasmodic and myotropic effect.

Pharmacokinetics

The drug is well absorbed from the gastrointestinal tract. Erespal's instructions indicate that after oral administration of 1 tablet, the maximum concentration of fenspiride in the blood is detected after 6 hours; the use of syrup determines the effective concentration after 2.5 hours. The half-life (T 1/2) is 12 hours, excreted mainly through the urinary system. system (up to 90%), a small part is excreted by the intestines (about 10%).

Indications for use

The drug is indicated in the complex treatment of respiratory tract diseases (upper and lower sections):

• pharyngitis;
• nasopharyngitis;
• laryngitis;
• tracheitis;
• tracheobronchitis;
• bronchitis (with or without chronic respiratory failure);
• bronchial asthma;
• respiratory symptoms of influenza, measles and whooping cough;
• sinusitis;
• otitis;
• respiratory infections, the symptom complex of which includes cough.

Contraindications

• Hypersensitivity reactions to the main or excipients of the drug.
• Tablets - up to 18 years
• Syrup - children under 2 years old

Use in pregnant and lactating women

The use of Erespal during pregnancy and lactation is not recommended due to limited clinical data on safety for these categories of people. However, therapy with Erespal and analogues during pregnancy is not a basis for artificial termination of pregnancy.

Dosage

	Erespal syrup	Erespal tablets
Adults and teenagers over 18 years of age	45-90 milliliters (3-6 tablespoons, respectively) per day.	1 tablet (80 mg) twice or thrice a day. The maximum daily dose is 240 mg (3 tablets).
Children over 2 years old - at the rate of 4 mg per 1 kg of weight.	Children up to 10 kg: 10-20 milliliters (2-4 teaspoons, respectively) per day. Children over 10 kg: 30-60 ml (2-4 tablespoons, respectively) per day.
special instructions	Taken before meals. Be sure to shake before use. For young children, adding to a bottle with food or drink is acceptable.	Take half an hour before meals with water.
Duration of treatment	Determined by the doctor

Side effect

• The main adverse reactions during therapy with Erespal are observed from the gastrointestinal tract: gastrointestinal disorders, pain in the epigastric region, nausea, vomiting, diarrhea and vomiting are somewhat less common.
• From the cardiovascular system, tachycardia, palpitations, and a non-critical drop in blood pressure are possible.
• On the part of the central nervous system, the development of drowsiness and dizziness is likely.
• Skin: urticaria, erythema, angioedema, itching, epidermal necrolysis of a toxic nature.
• General disorders: asthenic phenomena, increased fatigue.
• Extra for syrup: hypersensitivity reactions to Sunset Yellow S dye.

Overdose

If you take syrup or tablets in a dose of more than 2320 mg, immediately contact a medical facility. Symptoms: agitation or drowsiness, lethargy, nausea and vomiting, tachycardia with accelerated sinus rhythm.

Drug interactions

Due to the possibility of developing a side reaction in the form of a sedative effect, it is not recommended to combine Erespal with drugs that have sedative activity and alcohol.

special instructions

The presence of parabens in the syrup can provoke the development of allergic reactions (immediately after administration and delayed).

Patients with diabetes mellitus should take into account the presence of sucrose in the composition: in 1 tsp. - 3 g (0.3 XE), 1 tbsp. contains 9 g (0.9 XE).

During therapy with Erespal, due to possible sedative reactions, caution is required when driving vehicles, working with precision mechanisms and activities requiring high speed reactions.

Shelf life and storage

Valid for 3 years from the date of manufacture. Does not require special storage conditions. When storing the syrup, sediment is likely to settle, which disappears when shaken and does not affect the activity.

Erespal's analogs

Siresp, Eladon, Inspiron, Fosidal, Fenspiride.

A cough medicine with pronounced anti-inflammatory, antispasmodic and antihistamine effects. The main active ingredient of this drug is fenspiride. The use of Erespal reduces the formation of exudate - the accumulation of fluid in the tissues, causing the formation of edema. Available in the form of tablets and syrup for children.

The therapeutic effect of Erespal is aimed at eliminating negative inflammatory processes in the bronchi. The drug effectively removes bronchial secretions, preventing inflammation from spreading, and exhibits a number of myotropic and antispasmodic properties. Erespal is used to treat diseases that affect the respiratory system.

Instructions for use:

• Latin name: Eurespal
• ATX code: R03DX03
• Active ingredient: Fenspiride
• Manufacturer: Les Laboratoires Servier (France)

The description of the drug Erespal is not intended for prescribing treatment without the participation of a doctor.

Composition and release form

Erespal tablets

Excipients:

• povidone;
• hypromellose;
• calcium hydrogen phosphate;
• silicon dioxide;
• glycerol;
• titanium dioxide;
• magnesium stearate.

Erespal syrup for children

Contains 2 mg fenspiride hydrochloride per 1 ml.

Excipients:

• glycerol;
• methyl parahydroxybenzoate;
• licorice extract;
• potassium sorbate;
• sucrose;
• water;
• saccharin.

Pharmacological properties

Pharmacodynamics

The active substance of Erespal is fenspiride hydrochloride, which inhibits the metabolism of arachidonic acid, which promotes the development of inflammation in the lung tissue. The bronchodilating effect of fenspiride blocks H1 receptors of the bronchi, reducing the release of bradykinin, serotonin, histamine (biologically active mediators of inflammation). By blocking alpha-adrenergic receptors, fenspiride reduces sputum production. Erespal relieves dry cough by changing the rheological properties of bronchial secretions.

Pharmacokinetics

Erespal reaches the site of inflammation after absorption in the stomach. The effect of Erespal occurs 6 hours after taking the tablets. Erespal syrup acts much faster, the peak of action is observed within 2.5-3 hours after administration. The drug is excreted from the body by the kidneys, along with urine (90%), the remaining 10% is removed through the intestines.

Indications for use of Erespal

Diseases of the upper and lower respiratory tract:

• rhinopharyngitis and laryngitis;
• otitis and sinusitis, including allergic;
• rhinotracheobronchitis;
• bronchitis;
• bronchial asthma (maintenance therapy);
• respiratory phenomena in measles, whooping cough and influenza.

Directions for use and dosage

Erespal tablets

For adults Erespal is prescribed 80 mg (1 tablet) 2-3 or 3-6 tablespoons (45-90 ml) of syrup per day. 1 tablespoon of Erespal contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.

Erespal in tablet form is not intended for the treatment of children under 14 years of age.

Erespal syrup for children

For children 2-16 years - 2-4 tablespoons of Erespal syrup (30-60 ml). The course of treatment is 20-30 days. A repeated course is possible after consultation with a doctor.

The drug must be taken before meals. Shake the syrup before use.

Side effect

From the gastrointestinal tract

• nausea;
• stomach pain;
• vomit.

Allergic reactions

• rarely - erythema;
• Quincke's edema;
• fixed erythema pigmentosa, rash.

Due to the presence of para-hydroxybenzoate in the syrup, urticaria may develop.

Others

• drowsiness;
• rarely - moderate tachycardia, disappearing after discontinuation of the drug.

Contraindications for use

• children under 14 years of age (for tablets);
• the medication in the form of syrup is not prescribed to children under 2 years of age;
• hypersensitivity to the active substance or components of the drug.

Use during pregnancy and lactation

While taking Erespal during lactation need to stop breastfeeding, since there are no studies on the excretion of fenspiride in breast milk.

Special instructions for use

If the disease is infectious, Erespal is treated in combination with standard antibiotic therapy.

Erespal in the form of syrup is prescribed with caution to patients with hypersensitivity to acetylsalicylic acid and other NSAIDs due to the risk of allergic reactions (including bronchospasm) in this category of patients, since the syrup contains Sunset Yellow CFC dye.

Since the syrup contains sucrose, the drug must be prescribed to patients with diabetes mellitus with caution - dose adjustment of hypoglycemic drugs is necessary.

Due to the presence of sucrose, Erespal in syrup form is not prescribed to patients with fructose intolerance, glucose-galactose malabsorption syndrome or sucrazoisomaltase deficiency (a rare metabolic disorder).

Overdose

Symptoms

• drowsiness or agitation;
• nausea;
• vomit;
• sinus tachycardia.

Treatment

• gastric lavage;
• ECG monitoring.

Interaction with other drugs

Drug interactions with Erespal have not been described.

Conditions for dispensing from pharmacies

The drug is available with a doctor's prescription.

Storage conditions and periods

The drug must be stored out of the reach of children at a temperature not exceeding 25°C. The shelf life of tablets is 2 years, syrup - 3 years. Do not use after the expiration date indicated on the package.

Interaction with alcohol

You should not drink alcohol while treating Erespal, as there is a high risk of unwanted sedation.

Erespal's analogs

A structural analogue of Erespal is Fenspiride. But there are many medications that reduce swelling in inflamed tissues, treat coughs and expand the bronchial lumen.

The closest analogues of Erespal:

• Ambrobene;
• Inspiron;
• Lazolvan;
• Stoptussin;
• Thespalen;
• Eladon;
• Erispirus.

However, each of these drugs has its own characteristics. Therefore, you should not change the drug without the approval of your doctor.

Erespal price

Average prices for the drug:

• Erespal tablets 80 mg (30 pcs): 350 rubles;
• Erespal syrup 150 ml: 250 rubles.

Instructions for use Erespal positions the medicine as a drug with universal action against a number of diseases that usually accompany each other, for example, bronchitis and tonsillitis or colds and sinusitis.

Erespal syrup and tablets - description of the drug

The drug is available in two varieties: syrup and tablets.

1. Erespal 80 mg tablets- round, smooth, with convexities on the sides, in a film shell. They are packaged in blisters, 15 washers each. The packaging of the drug includes two blisters (30 tablets) and a detailed summary of the drug, describing its properties and recommended use.
2. Erespal syrup- This is a child form of the drug, it is produced in dark glass bottles with a volume of 150 ml. The medicine has a pleasant orange color, viscous consistency, smell and taste of honey. 1 ml of syrup contains 2 mg of the active substance fenspiride and a number of auxiliary components (extracts of rose, orange, vanilla, rum, honey). The bottles are additionally packaged in cardboard boxes, each of which has an insert with instructions.

The active component of the drug is fenspiride hydrochloride. In addition to this substance, which has a direct therapeutic effect, the drug contains auxiliary components that promote faster absorption of the medication and, accordingly, a faster therapeutic effect.

Operating principle and properties

Erespal is a drug that provides pronounced anti-inflammatory, antispasmodic and antihistamine effects. Its use significantly reduces the formation of exudate, that is, the accumulation of fluid in the tissues, causing the formation of edema. The drug also effectively removes inflammation, preventing inflammation from spreading, and exhibits a number of myotropic and antispasmodic properties.

The strong anti-inflammatory effect of the drug is due to the fact that fenspiride significantly inhibits processes associated with the metabolism of arachnidic acid, reduces the activity of serotonins, bradykinins and histamines, and also partially blocks a number of histamine receptors.

The active substance reduces the production of cytokines and free radicals, which are directly involved in the development of bronchospasm and the inflammatory process. In addition, fenspiride has an antispasmodic effect and blocks the activity of alpha-adrenergic receptors, which contribute to the formation of bronchial secretions and increase the risk of bronchial obstruction.

The medicine reaches the site of inflammation after absorption in the stomach. The highest content and maximum activity of Erespal occurs 6 hours after taking the tablets. Erespal syrup acts much faster, the peak of its activity is observed within 2.5-3 hours after administration. The drug is excreted from the body mainly by the kidneys, along with urine (90%), the remaining 10% is removed through the intestines.

Indications

Indications for the use of Erespal are chronic and acute forms of the following diseases:

• bronchitis, rhinotracheobronchitis;
• rhinitis (including allergic);
• nasopharyngitis;
• otitis;
• sinusitis;
• infectious diseases of the respiratory tract, accompanied by a debilitating cough;
• characteristic symptoms of whooping cough, measles, influenza (hoarseness, sore throat, cough);
• respiratory tract infections (in combination with antibacterial agents).

The attending physician may prescribe Erespal as part of complex therapy for complicated bronchial asthma and various respiratory diseases accompanied by cough and other respiratory phenomena. Indications for the use of Erespal syrup are exactly the same as for tablets. The doctor determines which form of the drug to give preference in a particular case.

Instructions for use

Good to know

When prescribing the drug, the patient's age, type of disease, severity of symptoms and a number of other factors should be taken into account.

• one tablet (80 mg of medication) twice a day;
• from 3 to 6 tablespoons (tablespoons) of syrup per day, that is, from 40 to 90 ml of medicine, divided into 2 doses, depending on age and other factors.

Can children take Erespal? Particular attention should be paid to the fact that treatment with tablets can only be carried out after reaching 14 years of age. Erespal for young children is used only in the form of syrup. The drug must be prescribed by a doctor, parents must strictly follow his recommendations and not exceed the indicated dosages.

Reception scheme

• if the child’s weight is less than 10 kilograms, the dose of the drug is 1-2 teaspoons twice a day;
• with a weight over 10 kilograms, the optimal dosage is from 1 to 3 large (tablespoons) spoons twice a day.

There are no time restrictions in treatment with this medication; how many days to take Erespal depends on the general condition of the patient and how quickly the process occurs.

Contraindications

Erespal is prohibited for use under the following conditions:

• immunity or personal intolerance to the components of the drug;
• syrup is not recommended for use by patients with diabetes;
• serious impairment of kidney function or severe forms of kidney disease;
• age up to 14 years (for tablets) and up to 2 years (for syrup).

Pregnancy, regardless of its duration, and the lactation period are also restrictions on taking the drug, since there is no reliable clinical data on the effect of the active substance on fetal development or the health of a breastfed infant.

Adverse reactions

The drug can cause a number of side effects, in which they either stop taking the pills and switch to syrup (or vice versa), or completely abandon Erespal therapy.

Side effects from taking the medicine are:

1. discomfort in the area of ​​epistragy;
2. nausea, slight dizziness;
3. feeling of restlessness;
4. urticaria, rashes, itching during allergic reactions;
5. signs of tachycardia.

Good to know

In exceptional cases, a dangerous reaction such as Quincke's edema may occur. In this case, you should immediately call emergency medical assistance.

In case of an overdose of the medicine, you should immediately consult a doctor, as the condition may be complicated by nausea, vomiting, severe drowsiness, or, on the contrary, agitation, manifestations of tachycardia (). The necessary assistance in case of overdose consists of gastric lavage, additionally doing an ECG and taking other measures necessary to maintain the vital functions of the body.

When treating with Erispal, the following rules should be observed:

• The drug should be taken strictly before meals, no less than 30-20 minutes;
• treatment cannot be combined with taking anti-inflammatory non-steroidal drugs (NSAIDs) and drugs based on acetylsalicylic acid, since this combination increases the risk of developing bronchospasm;
• you cannot be treated with sedatives and Erespal at the same time, as this leads to severe drowsiness, lethargy and weakness;
• Erespal should not be combined with alcohol, including alcohol-based medications;
• When treating diseases caused by infectious pathogens, you should simultaneously undergo a course of antibacterial therapy, which will be prescribed by the attending physician.

When using syrup, which many adult patients prefer to treat, due to its high activity and faster effect, you need to remember that each tablespoon contains 30 mg of fenspiride (the active element of the drug) and 9-11 g of sucrose, and each teaspoon contains 10 mg of hydrochloride fenspiride and 3-4 g of sucrose.

Persons suffering from or prone to this disease should not be treated with syrup. For this category of patients, it is safer to use Erespal tablets for coughs associated with problems with the respiratory system.

Many patients are interested in whether Erespal is an antibiotic?

In fact, it is a remedy that effectively suppresses the inflammatory process, but cannot replace antibacterial therapy. Therefore, if necessary, the drug is prescribed together with antibiotics.

Since Erespal can have a sedative effect associated with blocking histamine receptors, it is not recommended to be prescribed simultaneously with sedatives and tranquilizers.

Analogs

Erespal has only one structural analogue - Fenspiride. But there are quite a lot of medications similar in therapeutic effect to Erespal (that is, reducing swelling in inflamed tissues, treating coughs and expanding the bronchial lumen). The closest analogues of the drug:

• Eladon;
• Thespalen;
• Inspiron:
• Ambrobene;
• Lazolvan.

However, despite the similarities and general indications for use, each of the drugs has its own characteristics. Therefore, you should not change the drug without the approval of your doctor.

Price

What's good, Erespal, is that the medicine was developed and produced in France. This country has very high requirements for medicines, some of the most stringent in the world, so all the drugs produced by the French actually cure and have high safety characteristics.

Erespal can be purchased in the pharmacy chain without a prescription. Average prices for different forms of the drug:

1. Erespal tablets 80 mg (30 pcs) - from 350 rubles;
2. Erespal syrup 150ml - from 250 rubles.

The shelf life of the medicine is 3 years; the medicine must be stored at temperatures not exceeding 25 degrees Celsius. For open syrup, the bottom side shelf in the refrigerator is ideal.